=>Describe the experiment that Southam developed to test his
hypothesis about HeLa. Who were the test subjects in Southam’s first study?
Were they informed about the research and its risks? What was the result of
Southam’s first research study?
=> What does the term “informed consent” mean?
=>What was the result of the legal action taken against Southam
and Mandel? Explain how the action against Southam and Mandel led to the
development of informed consent forms as a standard medical practice.
=> Summarize the various ways that HeLa was used in the space
program. What disturbing discovery did scientists make about the way HeLa
responded in orbit?
What scientific discoveries were made possible as a result of
fused hybrid cells?
=>How did the public respond to the idea of cell hybrids? In
what specific ways did the media influence the public’s perception of cell
hybrids?
=> What did Stanley Gartler discover about eighteen of the most
commonly used cell cultures?
=>What unique abilities did HeLa have that allowed it to
contaminate cultures without researchers being aware that contamination had
occurred? Why would HeLa contamination be a problem for researchers?
=>What is “spontaneous transformation”? What did Gartler
suggest about spontaneous transformation?
=>How did the scientific community respond to Gartler’s theory
about HeLa contamination?
=> What are “night doctors?” Where did the term originate and
why? What do the Lackses believe “night doctors” do? Is their belief based on
real events? Explain your answer.
=> What does the 1969 Johns Hopkins study reveal about the
researcher’s attitude and assumptions about race?
=>
What is the Lacks family’s biggest complaint about the way they have been
treated by Johns Hopkins and Dr. Gey?
=> After finding out that his cancer was terminal, what reason
did Gey give for his decision to offer himself as a research subject?
=>What did Howard Jones realize when he reviewed Henrietta’s
medical records?
=>What was the purpose of President Nixon’s National Cancer
Act?
=> Do you agree that Henrietta should have been correctly
identified in order to “give her the fame she so richly deserves,” or do you
think her anonymity should have been protected? Explain your answer.
=>From a legal standpoint, how is the fact that the doctors
failed to obtain consent prior to taking blood from the Lacks family in 1973
different from their initial failure to obtain consent from Henrietta in 1951?
=>Why did advances in genetic research necessitate establishing
the legal requirement that doctors or researchers obtain informed consent
documentation prior to taking DNA samples from patients for research?
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